发明申请
- 专利标题： Amidino compounds as cysteine protease inhibitors
- 专利标题（中）： 脒基化合物作为半胱氨酸蛋白酶抑制剂
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申请号： US10583629申请日： 2004-12-22
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公开(公告)号： US20070105892A1公开(公告)日： 2007-05-10
- 发明人: Michael Graupe , Agnes Lau , Jiayao Li , John Link , Craig Mossman , Soon H. Woo , Sheila M. Zipfel
- 申请人： Michael Graupe , Agnes Lau , Jiayao Li , John Link , Craig Mossman , Soon H. Woo , Sheila M. Zipfel
- 申请人地址： US CA South San Francisco
- 专利权人： AXYS Pharmaceuticals, Inc.
- 当前专利权人： AXYS Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 国际申请： PCT/US04/43451 WO 20041222
- 主分类号： A61K31/4745
- IPC分类号： A61K31/4745 ; A61K31/4245 ; C07D491/02 ; C07D271/10
摘要：
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
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