发明申请
- 专利标题: Human antibodies
- 专利标题(中): 人抗体
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申请号: US11521060申请日: 2006-09-13
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公开(公告)号: US20070111259A1公开(公告)日: 2007-05-17
- 发明人: Joe Buechler , Gunars Valkirs , Jeff Gray , Nils Lonberg
- 申请人: Joe Buechler , Gunars Valkirs , Jeff Gray , Nils Lonberg
- 申请人地址: US NJ Princeton
- 专利权人: Medarex, Inc.
- 当前专利权人: Medarex, Inc.
- 当前专利权人地址: US NJ Princeton
- 主分类号: C40B30/06
- IPC分类号: C40B30/06 ; C40B50/06 ; C40B40/10
摘要:
The invention uses the power of display selection methods to screen libraries of human immunoglobulin genes from nonhuman transgenic animals expressing human immunoglobulins. Such screening produces unlimited numbers of high affinity human antibodies to any target of interest.
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