发明申请
US20070112523A1 Ligands for 17i as modulators of orthopox viruses and methods for discovery thereof
审中-公开
17i配体作为正痘病毒的调节剂及其发现方法
- 专利标题： Ligands for 17i as modulators of orthopox viruses and methods for discovery thereof
- 专利标题（中）： 17i配体作为正痘病毒的调节剂及其发现方法
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申请号： US10581840申请日： 2004-12-10
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公开(公告)号： US20070112523A1公开(公告)日： 2007-05-17
- 发明人: Adnan Mjalli , Mohan Rao , Murty Arimilli , Robert Andrews , Robert Rothlein
- 申请人： Adnan Mjalli , Mohan Rao , Murty Arimilli , Robert Andrews , Robert Rothlein
- 专利权人： TransTech Phama,Inc.
- 当前专利权人： TransTech Phama,Inc.
- 国际申请： PCT/US04/41329 WO 20041210
- 主分类号： G06F19/00
- IPC分类号： G06F19/00
摘要：
Disclosed are structural coordinates that define the three-dimensional (3D) structure of I7L proteinase and methods by which the coordinates may be used to develop compounds that bind to, and/or modulate, I7L. The technology described herein may be applied to the development of antiviral compounds that target I7L, or may be used to develop target compound that may bind to, and/or modify the catalytic activity of, other proteins.
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