发明申请
- 专利标题： Agents and methods for analyzing protein interactions
- 专利标题（中）： 用于分析蛋白质相互作用的试剂和方法
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申请号： US11305970申请日： 2005-12-19
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公开(公告)号： US20070140967A1公开(公告)日： 2007-06-21
- 发明人: Nichole Wood , Mohan Amaratunga , Hans Grade , Faisal Syud , Anup Sood , Reginald Smith , Ayse Dinc , Amy Williams , Anthony Murray , Gregory Goddard
- 申请人： Nichole Wood , Mohan Amaratunga , Hans Grade , Faisal Syud , Anup Sood , Reginald Smith , Ayse Dinc , Amy Williams , Anthony Murray , Gregory Goddard
- 主分类号： A61K51/00
- IPC分类号： A61K51/00
摘要：
Agents and methods for qualitative and quantitative analysis a protein complex or protein complexes using isotope-labeled symmetrical bifunctional crosslinkers and mass spectrometry are provided. Targeting moieties, cell permeability moieties, or affinity moieties, may be appended to the bifunctional crosslinkers. The isotope-labeled symmetrical bifunctional crosslinkers may be used in a kit or as a library.
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