发明申请
- 专利标题： Pyridinamide derivatives as kinase inhibitors
- 专利标题（中）： 吡啶酰胺衍生物作为激酶抑制剂
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申请号： US10590724申请日： 2005-01-13
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公开(公告)号： US20070142440A1公开(公告)日： 2007-06-21
- 发明人: Lars Burgdorf , Hans-Peter Buchstaller , Frank Stieber , Christiane Amendt , Hartmut Greiner , Matthias Grell , Christ8an Sirrenberg , Frank Zenke
- 申请人： Lars Burgdorf , Hans-Peter Buchstaller , Frank Stieber , Christiane Amendt , Hartmut Greiner , Matthias Grell , Christ8an Sirrenberg , Frank Zenke
- 优先权： DE102004009238.9 20040226
- 国际申请： PCT/EP05/00273 WO 20050113
- 主分类号： C07D211/84
- IPC分类号： C07D211/84 ; A61K31/4412
摘要：
The invention relates to substituted arylamide derivatives of the formula I, the preparation and use thereof for the preparation of a medicament for the treatment of diseases, in particular tumours and/or diseases that are caused, mediated and/or propagated by angiogenesis. Compounds of the formula I are effective inhibitors of tyrosine kinases, in particular TIE-2 and VEGFR, and of Raf kinases.
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