发明申请
- 专利标题: Optimized anti-CD30 antibodies
- 专利标题(中): 优化抗CD30抗体
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申请号: US11544165申请日: 2006-10-06
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公开(公告)号: US20070148171A1公开(公告)日: 2007-06-28
- 发明人: Gregory Lazar , John Desjarlais , Philip Hammond , David Carmichael , Bao-lu Chen , Seung Chu , Sher Karki
- 申请人: Gregory Lazar , John Desjarlais , Philip Hammond , David Carmichael , Bao-lu Chen , Seung Chu , Sher Karki
- 申请人地址: US CA Monrovia
- 专利权人: XENCOR, INC.
- 当前专利权人: XENCOR, INC.
- 当前专利权人地址: US CA Monrovia
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/28
摘要:
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
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