发明申请
- 专利标题： Infectious bronchitis virus with an altered spike gene
- 专利标题（中）： 传染性支气管炎病毒具有改变的穗基因
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申请号： US10547219申请日： 2004-03-03
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公开(公告)号： US20070154489A1公开(公告)日： 2007-07-05
- 发明人: David Cavanagh , Paul Britton , Ian Tarpey
- 申请人： David Cavanagh , Paul Britton , Ian Tarpey
- 优先权： EP03075623.3 20030303
- 国际申请： PCT/EP04/50247 WO 20040303
- 主分类号： A61K39/12
- IPC分类号： A61K39/12
摘要：
The present invention provides a vaccine for use in the protection of poultry against infectious bronchitis comprising an attenuated infectious bronchitis virus (IBV) and a pharmaceutical acceptable carrier or diluent, characterized in that the attenuated IBV comprises a heterologous spike gene. Such a vaccine is based on IBV strain Beaudette that is able to express a spike gone derived from a different IBV strain. The vaccines provided by the present invention also allow the administration via the in ovo route.
公开/授权文献
- US07445785B2 Infectious bronchitis virus with an altered spike gene 公开/授权日：2008-11-04
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