Invention Application
- Patent Title: Heterobicyclic metalloprotease inhibitors
- Patent Title (中): 异双环金属蛋白酶抑制剂
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Application No.: US11602140Application Date: 2006-11-20
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Publication No.: US20070155738A1Publication Date: 2007-07-05
- Inventor: Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochguertel , Michael Essers , Joshua Van Veldhuizen , Bert Nolte , Brian Gallagher , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Biesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur Taveras
- Applicant: Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochguertel , Michael Essers , Joshua Van Veldhuizen , Bert Nolte , Brian Gallagher , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Biesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur Taveras
- Assignee: ALANTOS PHARMACEUTICALS, INC.
- Current Assignee: ALANTOS PHARMACEUTICALS, INC.
- Main IPC: A61K31/538
- IPC: A61K31/538 ; A61K31/5377 ; A61K31/519 ; C07D491/04 ; C07D487/04
Abstract:
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
Information query
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