- 专利标题： COMPOSITIONS AND THEIR USES DIRECTED TO IL-4R ALPHA
-
申请号： US11548650申请日： 2006-10-11
-
公开(公告)号： US20070161593A1公开(公告)日： 2007-07-12
- 发明人: James Karras , Susan Gregory , Susan Freier , William Gaarde , Mausumee Guha
- 申请人： James Karras , Susan Gregory , Susan Freier , William Gaarde , Mausumee Guha
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02 ; C07F9/6533
摘要：
Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation.
公开/授权文献
- US07507810B2 Compositions and their uses directed to IL-4R alpha 公开/授权日：2009-03-24
信息查询
