发明申请
- 专利标题: Method of treating neurodegenerative disease
- 专利标题(中): 治疗神经变性疾病的方法
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申请号: US11548890申请日: 2006-10-12
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公开(公告)号: US20070161595A1公开(公告)日: 2007-07-12
- 发明人: David Bumcrot , Matthew Farrer , Demetrius Maraganore , Hans-Peter Vornlocher
- 申请人: David Bumcrot , Matthew Farrer , Demetrius Maraganore , Hans-Peter Vornlocher
- 申请人地址: US MN Rochester US MA Cambridge
- 专利权人: Mayo Foundation for Medical Education and Research,Alnylam Pharmaceuticals, Inc.
- 当前专利权人: Mayo Foundation for Medical Education and Research,Alnylam Pharmaceuticals, Inc.
- 当前专利权人地址: US MN Rochester US MA Cambridge
- 主分类号: A61K48/00
- IPC分类号: A61K48/00
摘要:
Aspects featured in the invention relate to compositions and methods for inhibiting alpha-synuclein (SNCA) gene expression, such as for the treatment of neurodegenerative disorders. An anti-SNCA agent featured herein that targets the SNCA gene can have been modified to alter distribution in favor of neural cells.
公开/授权文献
- US07595306B2 Method of treating neurodegenerative disease 公开/授权日:2009-09-29
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