发明申请
US20070161690A1 Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
有权
抑制BCL蛋白与结合配偶体相互作用的化合物和方法
- 专利标题： Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
- 专利标题（中）： 抑制BCL蛋白与结合配偶体相互作用的化合物和方法
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申请号： US11600332申请日： 2006-11-15
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公开(公告)号： US20070161690A1公开(公告)日： 2007-07-12
- 发明人: Alfredo Castro , Edward Holson , Brian Hopkins , Nii Koney , Daniel Snyder , Thomas Tibbitts
- 申请人： Alfredo Castro , Edward Holson , Brian Hopkins , Nii Koney , Daniel Snyder , Thomas Tibbitts
- 申请人地址： US MA Cambridge
- 专利权人： Infinity Pharmaceuticals, Inc.
- 当前专利权人： Infinity Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/42
- IPC分类号： A61K31/42 ; C07D413/02 ; C07D261/02
摘要：
One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
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