- 专利标题： Compounds for the treatment of proliferative disorders
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申请号： US11601590申请日： 2006-11-17
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公开(公告)号： US20070179159A1公开(公告)日： 2007-08-02
- 发明人: Lijun Sun , Jun Jiang , Christopher Borella , Shoujun Chen , Keizo Koya
- 申请人： Lijun Sun , Jun Jiang , Christopher Borella , Shoujun Chen , Keizo Koya
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K31/4439 ; A61K31/425 ; C07F9/06 ; C07F9/6512 ; C07D417/02
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US07572821B2 Compounds for the treatment of proliferative disorders 公开/授权日：2009-08-11
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