发明申请
- 专利标题: Method of searching substrate having antidiabetic activity
- 专利标题(中): 检索具有抗糖尿病活性的底物的方法
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申请号: US10514119申请日: 2003-05-16
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公开(公告)号: US20070191402A1公开(公告)日: 2007-08-16
- 发明人: Hiroki Ishiguro , Yuko Saeki , Seiji Sugimoto , Masahiro Matsubara , Kimihisa Ueno , Kiyotoshi Mori , Satoshi Nakanishi , Hiroshi Yano
- 申请人: Hiroki Ishiguro , Yuko Saeki , Seiji Sugimoto , Masahiro Matsubara , Kimihisa Ueno , Kiyotoshi Mori , Satoshi Nakanishi , Hiroshi Yano
- 申请人地址: JP Chiyoda-ku 100-8185
- 专利权人: KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人: KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人地址: JP Chiyoda-ku 100-8185
- 优先权: JP2002-143599 20020517
- 国际申请: PCT/JP03/06137 WO 20030516
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K31/53 ; C07D487/12 ; G01N33/53
摘要:
The present invention provides a screening method of a substance which inhibits binding of a condensed purine derivative to a pancreatic β cell or a treated product of the cell, a substance which inhibits binding of a condensed purine derivative to a protein capable of the condensed purine derivative, and a substance which inhibits the expression or enzymatic activity of a protein capable of a condensed purine derivative, which comprises using the condensed purine derivative and a pancreatic β cell or a treated product of the cell or a protein capable of binding to the condensed purine derivative.
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