发明申请
US20070191639A1 Optically active 1-Aryl-2-fluoro-substituted ethylamine and method for producing same
有权
光活性1-芳基-2-氟取代的乙胺及其制备方法
- 专利标题： Optically active 1-Aryl-2-fluoro-substituted ethylamine and method for producing same
- 专利标题（中）： 光活性1-芳基-2-氟取代的乙胺及其制备方法
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申请号： US10591669申请日： 2005-02-21
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公开(公告)号： US20070191639A1公开(公告)日： 2007-08-16
- 发明人: Akihiro Ishii , Masatomi Kanai , Yokusu Kuriyama , Manabu Yasumoto , Kenjin Inomiya , Takashi Ootsuka , Katsuhide Suto , Koji Ueda
- 申请人： Akihiro Ishii , Masatomi Kanai , Yokusu Kuriyama , Manabu Yasumoto , Kenjin Inomiya , Takashi Ootsuka , Katsuhide Suto , Koji Ueda
- 申请人地址： JP Yamaguchi 755-0001
- 专利权人： CENTRAL GLASS COMPANY, LIMITED
- 当前专利权人： CENTRAL GLASS COMPANY, LIMITED
- 当前专利权人地址： JP Yamaguchi 755-0001
- 优先权： JP2004-062735 20040305
- 国际申请： PCT/JP05/02740 WO 20050221
- 主分类号： C07C209/26
- IPC分类号： C07C209/26
摘要：
The present invention relates to a method of producing an optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [2] or a salt thereof by hydrogenolysis of an optically active secondary amine compound of the formula [1] or a salt thereof in the presence of a transition metal catalyst of Group VIII [Chem. 59] [where Ar represents an aryl group; n represents an integer of 1 or 2; and * represents an asymmetric carbon] [Chem. 60] [where Ar represents an aryl group; n represents an integer of 1 or 2; and * represents an asymmetric carbon].