发明申请
US20070197613A1 2-{-3,'2-(PHENYL)-OXAZOL-4-YLMETHOXYL-CYCLOHEXYL METHOXY}-PROPIONIC ACID DERIVATIVES USED AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) LIGANDS FOR THE TREATMENT OF HYPERLIPIDEMIA AND DIABETES
有权
用于治疗高脂血症和糖尿病的过氧化物酶促反应激活受体（PPAR）配体的2-（-3 - ， - 2-（苯基） - 唑-4-基甲氧基 - 环己基甲氧基} - 丙酸衍生物
- 专利标题： 2-{-3,'2-(PHENYL)-OXAZOL-4-YLMETHOXYL-CYCLOHEXYL METHOXY}-PROPIONIC ACID DERIVATIVES USED AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) LIGANDS FOR THE TREATMENT OF HYPERLIPIDEMIA AND DIABETES
- 专利标题（中）： 用于治疗高脂血症和糖尿病的过氧化物酶促反应激活受体（PPAR）配体的2-（-3 - ， - 2-（苯基） - 唑-4-基甲氧基 - 环己基甲氧基} - 丙酸衍生物
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申请号： US11671673申请日： 2007-02-06
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公开(公告)号： US20070197613A1公开(公告)日： 2007-08-23
- 发明人: Heiner Glombik , Christian Stapper , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Knieps
- 申请人： Heiner Glombik , Christian Stapper , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Knieps
- 申请人地址： DE Frankfurt 65929
- 专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人地址： DE Frankfurt 65929
- 优先权： DE102004039532.2 20040814
- 主分类号： C07D263/30
- IPC分类号： C07D263/30 ; A61K31/421
摘要：
The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistence and the like comprising acetic acid derivatives with cyclohexylmethoxy substituents and their salts. Known as peroxisome proliferator-activated receptors (PPAR) agonists/antagonists, the invention relates to compounds of formula I wherein the various substituent R-groups are more specifically defined herein.
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