发明申请
US20070202550A1 Novel G protein-coupled receptor protein, its DNA and ligand thereof
失效
新型G蛋白偶联受体蛋白,其DNA及其配体
- 专利标题: Novel G protein-coupled receptor protein, its DNA and ligand thereof
- 专利标题(中): 新型G蛋白偶联受体蛋白,其DNA及其配体
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申请号: US11701719申请日: 2007-02-02
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公开(公告)号: US20070202550A1公开(公告)日: 2007-08-30
- 发明人: Takuya Watanabe , Kuniko Kikuchi , Yasuko Terao , Yasushi Shintani , Shuji Hinuma , Shoji Fukusumi , Ryo Fujii , Masaki Hosoya , Chieko Kitada
- 申请人: Takuya Watanabe , Kuniko Kikuchi , Yasuko Terao , Yasushi Shintani , Shuji Hinuma , Shoji Fukusumi , Ryo Fujii , Masaki Hosoya , Chieko Kitada
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company, Ltd.
- 当前专利权人: Takeda Pharmaceutical Company, Ltd.
- 当前专利权人地址: JP Osaka
- 优先权: JP11/259818 19990914; JP11/221640 19990804; JP11/166672 19990614; JP11/106812 19990414; JP11/60030 19990308; JP10/323,759 19991113
- 主分类号: G01N33/567
- IPC分类号: G01N33/567 ; C07H21/04 ; C07K14/47 ; C07K16/28 ; C12N15/63 ; C12N5/10 ; C12P21/00
摘要:
The polypeptides in the present invention possess the effects of promoting and inhibiting the secretion of prolactin, and are thus useful as drugs for the prevention and treatment of various diseases, in terms of prolactin secretion stimulants, which are associated with the secretion of prolactin, such as hypoovarianism, spermatic underdevelopment, menopausal symptoms, hypothyroidism, etc. The polypeptides are useful as drugs for the prevention and treatment of various diseases, in terms of prolactin secretion inhibitors, which are associated with the secretion of prolactin, such as pituitary tumor, diencephalon tumor, menstrual disorder, autoimmune diseases, prolactinoma, sterility, impotence, amenorrhea, lactorrhea, acromegaly, Chiari-Frommel syndrome, Argonz-del Castilo syndrome, Forbes-Albright syndrome, lymphoma, Sheehan's syndrome, spermatogenesis disorder, etc.
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