发明申请
US20070203057A1 COMPOUNDS AND METHODS FOR MODULATING ADHESION MOLECULE FUNCTION
审中-公开
用于调节粘合分子功能的化合物和方法
- 专利标题： COMPOUNDS AND METHODS FOR MODULATING ADHESION MOLECULE FUNCTION
- 专利标题（中）： 用于调节粘合分子功能的化合物和方法
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申请号： US11616733申请日： 2006-12-27
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公开(公告)号： US20070203057A1公开(公告)日： 2007-08-30
- 发明人: Patrick Doherty , Orest Blaschuk , Barbara Gour
- 申请人： Patrick Doherty , Orest Blaschuk , Barbara Gour
- 申请人地址： CA Ottawa K2K 3G4
- 专利权人： ADHEREX TECHNOLOGIES, INC.
- 当前专利权人： ADHEREX TECHNOLOGIES, INC.
- 当前专利权人地址： CA Ottawa K2K 3G4
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; A61K38/00
摘要：
Modulating agents and methods for enhancing or inhibiting cadherin-mediated functions are provided. The modulating agents comprise at least an HAV binding motif, an analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a motif. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material.
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