发明申请
- 专利标题： ER-beta-selective ligands
- 专利标题（中）： ER-β选择性配体
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申请号： US11247537申请日： 2005-10-11
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公开(公告)号： US20070208066A1公开(公告)日： 2007-09-06
- 发明人: Bernard Barlaam , Peter Bernstein , Cathy Dantzman , Paul Warwick
- 申请人： Bernard Barlaam , Peter Bernstein , Cathy Dantzman , Paul Warwick
- 优先权： SE0004825-6 20001222; SE0004826-4 20001222
- 主分类号： A61K31/41
- IPC分类号： A61K31/41 ; A61K31/423 ; A61K31/428 ; C07D263/52 ; C07D277/60
摘要：
Compounds of the formula (I) for use as an estrogen receptor -β-selective ligand are described wherein: X is O or S; and R1, R3-R6 are as described in the specification. The use of these compounds in treating Alzheimer's disease, anxiety disorders, depressive disorders, osteoporosis, cardiovascular disease, rheumatoid arthritis and prostate cancer is described; as are processes for making them.
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