Invention Application
US20070219211A1 Bicyclic Heterocyclic Derivatives and Their Use as Inhibitors of Stearoyl-Coadesaturase (Scd)
失效
双环杂环衍生物及其作为硬脂酰辅酶S（STD）抑制剂的用途
- Patent Title: Bicyclic Heterocyclic Derivatives and Their Use as Inhibitors of Stearoyl-Coadesaturase (Scd)
- Patent Title (中): 双环杂环衍生物及其作为硬脂酰辅酶S（STD）抑制剂的用途
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Application No.: US11575643Application Date: 2005-09-20
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Publication No.: US20070219211A1Publication Date: 2007-09-20
- Inventor: Rajender Kamboj , Jian-Min Fu , Vishnumurthy Kodumuru , Shifeng Liu , Kashinath Sadalapure , Nagasree Chakka , Duanjie Hou , Shaoyi Sun
- Applicant: Rajender Kamboj , Jian-Min Fu , Vishnumurthy Kodumuru , Shifeng Liu , Kashinath Sadalapure , Nagasree Chakka , Duanjie Hou , Shaoyi Sun
- Applicant Address: CA BC Burnaby V5G 4W8
- Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee Address: CA BC Burnaby V5G 4W8
- International Application: PCT/US05/33738 WO 20050920
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/497 ; C07D403/00 ; C12N9/99
Abstract:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise, for example, administering to a mammal in need thereof a compound of formula (I): where x, y, J, K, L, M, W, V, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Public/Granted literature
- US07547698B2 Bicyclic heterocyclic derivatives and their use as inhibitors of stearoyl-coadesaturase (SCD) Public/Granted day:2009-06-16
Information query
