发明申请
- 专利标题： Tetrahydro-pyrimidoazepines as modulators of TRPV1
- 专利标题（中）： 四氢嘧啶氮杂作为TRPV1的调节剂
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申请号： US11726756申请日： 2007-03-21
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公开(公告)号： US20070225275A1公开(公告)日： 2007-09-27
- 发明人: Brett Allison , Bryan Branstetter , James Breitenbucher , Michael Hack , Natalie Hawryluk , Alec Lebsack , Kelly McClure , Jeffrey Merit
- 申请人： Brett Allison , Bryan Branstetter , James Breitenbucher , Michael Hack , Natalie Hawryluk , Alec Lebsack , Kelly McClure , Jeffrey Merit
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; C07D487/02
摘要：
Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be-administered to treat, e.g., pain, itch, cough, asthma, or inflammatory bowel disease.
公开/授权文献
- US08673895B2 Tetrahydro-pyrimidoazepines as modulators of TRPV1 公开/授权日：2014-03-18