发明申请
- 专利标题: Induction of Insulin Secreting Cell
- 专利标题(中): 诱导胰岛素分泌细胞
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申请号: US11628202申请日: 2005-05-26
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公开(公告)号: US20070231897A1公开(公告)日: 2007-10-04
- 发明人: Susumu Seino , Kohtaro Minami , Masaaki Okuno , Kazumasa Miyawaki
- 申请人: Susumu Seino , Kohtaro Minami , Masaaki Okuno , Kazumasa Miyawaki
- 申请人地址: JP KYOTO JAPAN 6068501 JP HYOGO JAPAN 6590021
- 专利权人: KYOTO UNIVERSITY,JCR PHARMACEUTICALS CO., LTD.
- 当前专利权人: KYOTO UNIVERSITY,JCR PHARMACEUTICALS CO., LTD.
- 当前专利权人地址: JP KYOTO JAPAN 6068501 JP HYOGO JAPAN 6590021
- 优先权: JP2004-165367 20040603
- 国际申请: PCT/JP05/09613 WO 20050526
- 主分类号: C12N5/08
- IPC分类号: C12N5/08 ; C12N5/02
摘要:
Disclosed is a method for producing insulin secreting cells to be used in cell transplantation therapy of diabetes, by induction from pancreatic acinar cells in culture vessels. The method comprises culturing pancreatic acinar cells isolated from a mammal in a medium containing a growth factor, preferably epidermal growth factor, fibroblast growth factor and/or hepatocyte growth factor, to induce insulin secreting cells.
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