Induction of Insulin Secreting Cell
    1.
    发明申请
    Induction of Insulin Secreting Cell 审中-公开
    诱导胰岛素分泌细胞

    公开(公告)号:US20070231897A1

    公开(公告)日:2007-10-04

    申请号:US11628202

    申请日:2005-05-26

    IPC分类号: C12N5/08 C12N5/02

    摘要: Disclosed is a method for producing insulin secreting cells to be used in cell transplantation therapy of diabetes, by induction from pancreatic acinar cells in culture vessels. The method comprises culturing pancreatic acinar cells isolated from a mammal in a medium containing a growth factor, preferably epidermal growth factor, fibroblast growth factor and/or hepatocyte growth factor, to induce insulin secreting cells.

    摘要翻译: 公开了通过从培养容器中的胰腺腺泡细胞诱导,用于产生用于糖尿病的细胞移植治疗的胰岛素分泌细胞的方法。 该方法包括在含有生长因子,优选表皮生长因子,成纤维细胞生长因子和/或肝细胞生长因子的培养基中培养从哺乳动物分离的胰腺腺泡细胞,以诱导胰岛素分泌细胞。