- 专利标题: Novel compounds that are ERK inhibitors
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申请号: US11705709申请日: 2007-02-13
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公开(公告)号: US20070232610A1公开(公告)日: 2007-10-04
- 发明人: Yongqi Deng , Gerald Shipps , Alan Cooper , Yang Nan , Tong Wang , M. Siddiqui , Hugh Zhu , Robert Sun , Joseph Kelly , Ronald Doll , Jagdish Desai , James Wang , Youhao Dong , Vincent Madison , Li Xiao , Alan Hruza , Neng-Yang Shih
- 申请人: Yongqi Deng , Gerald Shipps , Alan Cooper , Yang Nan , Tong Wang , M. Siddiqui , Hugh Zhu , Robert Sun , Joseph Kelly , Ronald Doll , Jagdish Desai , James Wang , Youhao Dong , Vincent Madison , Li Xiao , Alan Hruza , Neng-Yang Shih
- 主分类号: A61K31/53
- IPC分类号: A61K31/53 ; A61K31/506 ; A61K31/502 ; A61K31/497 ; A61K31/4439 ; A61K31/407 ; A61K31/401 ; C07D403/02
摘要:
Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
公开/授权文献
- US07807672B2 Compounds that are ERK inhibitors 公开/授权日:2010-10-05
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