Invention Application
- Patent Title: INDOLE-TYPE DERIVATIVES AS INHIBITORS OF P38 KINASE
- Patent Title (中): 作为P38激酶的抑制剂的吲哚型衍生物
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Application No.: US11752255Application Date: 2007-05-22
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Publication No.: US20070232617A1Publication Date: 2007-10-04
- Inventor: Sarvajit Chakravarty , Sundeep Dugar , Qing Lu , Gregory Luedtke , Babu Mavunkel , John Perumattam , Richard Tester
- Applicant: Sarvajit Chakravarty , Sundeep Dugar , Qing Lu , Gregory Luedtke , Babu Mavunkel , John Perumattam , Richard Tester
- Applicant Address: US CA Mountain View
- Assignee: Scios, Inc.
- Current Assignee: Scios, Inc.
- Current Assignee Address: US CA Mountain View
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/445 ; C07D401/02 ; C07D403/02
Abstract:
The invention is directed to methods to inhibit p38-α kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.
Public/Granted literature
- US07488744B2 Indole-type derivatives as inhibitors of p38 kinase Public/Granted day:2009-02-10
Information query
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