发明申请
- 专利标题: 6-MODIFIED BICYCLIC NUCLEIC ACID ANALOGS
- 专利标题(中): 6改性双相核酸类似物
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申请号: US11627964申请日: 2007-01-27
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公开(公告)号: US20070249049A1公开(公告)日: 2007-10-25
- 发明人: Eric Swayze , Punit Seth
- 申请人: Eric Swayze , Punit Seth
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; C07H19/00 ; C12N5/00
摘要:
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
公开/授权文献
- US07399845B2 6-modified bicyclic nucleic acid analogs 公开/授权日:2008-07-15
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