发明申请
US20070249705A1 N-(1-(2,3-Dihydro-1H-Inden-5Yl)-2-Oxo-3-Pyrrolidinyl)-Sulfonamide Derivatives for Use as Factor Xa Inhibitors
审中-公开
用作因子Xa抑制剂的N-（1-（2,3-二氢-1H-茚-5-基）-2-氧代-3-吡咯烷基） - 磺酰胺衍生物
- 专利标题： N-(1-(2,3-Dihydro-1H-Inden-5Yl)-2-Oxo-3-Pyrrolidinyl)-Sulfonamide Derivatives for Use as Factor Xa Inhibitors
- 专利标题（中）： 用作因子Xa抑制剂的N-（1-（2,3-二氢-1H-茚-5-基）-2-氧代-3-吡咯烷基） - 磺酰胺衍生物
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申请号： US11574694申请日： 2005-09-02
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公开(公告)号： US20070249705A1公开(公告)日： 2007-10-25
- 发明人: John Harling , Savvas Kleanthous , Nigel Watson , Robert West , Robert Young
- 申请人： John Harling , Savvas Kleanthous , Nigel Watson , Robert West , Robert Young
- 优先权： GB0419744.8 20040906
- 国际申请： PCT/EP05/09517 WO 20050902
- 主分类号： A61K31/402
- IPC分类号： A61K31/402 ; A61K31/4025 ; A61K31/404 ; A61P7/02 ; C07D207/273 ; C07D403/12 ; C07D403/14 ; C07D405/12 ; C07D409/12
摘要：
The invention relates to at least one chemical entity chosen from compounds of formula (I): and pharmaceutically acceptable derivative(s) thereof. The invention also relates to processes for the preparation of compound(s) of formula (I), pharmaceutical compositions containing compound(s) of formula (I) and to the use of compound(s) of formula (I) in medicine, particularly in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
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