发明申请
- 专利标题: Inhibitors of checkpoint kinases
- 专利标题(中): 检测点激酶抑制剂
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申请号: US11789288申请日: 2007-04-24
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公开(公告)号: US20070254879A1公开(公告)日: 2007-11-01
- 发明人: Kenneth L. Arrington , Edward J. Brnardic , Vadim Y. Dudkin , Mark E. Fraley , Shaei Y. Huang , Cheng Wang
- 申请人: Kenneth L. Arrington , Edward J. Brnardic , Vadim Y. Dudkin , Mark E. Fraley , Shaei Y. Huang , Cheng Wang
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/506 ; A61K31/4745 ; C07D471/04
摘要:
The instant invention provides for compounds which comprise substituted triazoloquinazolinones that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.
公开/授权文献
- US07501435B2 Inhibitors of checkpoint kinases 公开/授权日:2009-03-10
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