发明申请
- 专利标题： TRIARYL COMPOUNDS AND DERIVATES THEREOF
- 专利标题（中）： 三环化合物及其衍生物
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申请号： US11737475申请日： 2007-04-19
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公开(公告)号： US20070254957A1公开(公告)日： 2007-11-01
- 发明人: Francis WILSON , Alison Reid , Valerie Reader , Richard Harrison , Mihiro Sunose , Remedios Hernandez-Perni , Jeremy Major , Cyrille Boussard , Kathryn Smelt , Jess Taylor , Adeline LeFormal , Andrew Cansfield , Svenja Burckhardt , Yan Zhang , Chih Ho
- 申请人： Francis WILSON , Alison Reid , Valerie Reader , Richard Harrison , Mihiro Sunose , Remedios Hernandez-Perni , Jeremy Major , Cyrille Boussard , Kathryn Smelt , Jess Taylor , Adeline LeFormal , Andrew Cansfield , Svenja Burckhardt , Yan Zhang , Chih Ho
- 优先权： EP06112934.2 20060421
- 主分类号： A61K31/192
- IPC分类号： A61K31/192 ; C07C59/40 ; C07C62/30
摘要：
The present invention relates to compounds having the general formula (I) with the definitions of X, Y, R1, R2, R3, R4, R9, R10 given below, and solvates, hydrates, esters, and pharmaceutically acceptable salts thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of γ-secretase activity.
公开/授权文献
- US08106236B2 Triaryl compounds and derivates thereof 公开/授权日：2012-01-31