发明申请
- 专利标题: Cyclic Natriuretic Peptide Constructs
- 专利标题(中): 循环利钠肽构建体
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申请号: US11694260申请日: 2007-03-30
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公开(公告)号: US20070265206A1公开(公告)日: 2007-11-15
- 发明人: Shubh Sharma , Margarita Bastos , Wei Yang , Hui-Zhi Cai
- 申请人: Shubh Sharma , Margarita Bastos , Wei Yang , Hui-Zhi Cai
- 申请人地址: US NJ Cranbury 08512
- 专利权人: PALATIN TECHNOLOGIES, INC.
- 当前专利权人: PALATIN TECHNOLOGIES, INC.
- 当前专利权人地址: US NJ Cranbury 08512
- 主分类号: A61K38/10
- IPC分类号: A61K38/10 ; A61K38/08 ; A61P5/00 ; A61P9/04 ; C07K7/02 ; C07K7/06 ; C07K7/08 ; C07K7/50
摘要:
Cyclic constructs with an N-terminus and a C-terminus which bind to a natriuretic peptide receptor and include a plurality of amino acid residues, at least one amino acid surrogate of formula I: where R, R′, Q, Y, W, Z, J, x and n are as defined in the specification, and optionally at least one prosthetic group, pharmaceutical compositions including such cyclic constructs, and methods of treating congestive heart failure or other conditions, syndromes or diseases for which induction of anti-hypertensive, cardiovascular, renal or endocrine effects are desired.
公开/授权文献
- US07622440B2 Cyclic natriuretic peptide constructs 公开/授权日:2009-11-24