发明申请
- 专利标题： Corneal Epithelial Sheet, Method Of constructing The Same, And Transplantation Method Using The Sheet
- 专利标题（中）： 角膜上皮片，构造方法和使用片材的移植方法
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申请号： US10592114申请日： 2005-02-14
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公开(公告)号： US20070280993A1公开(公告)日： 2007-12-06
- 发明人: Kouji Hashimoto , Yuuji Shirakata , Yuuichi Ohashi , Junji Hamuro
- 申请人： Kouji Hashimoto , Yuuji Shirakata , Yuuichi Ohashi , Junji Hamuro
- 申请人地址： JP Kobe-city JP Touon-shi
- 专利权人： ARBLAST CO., LTD.,,Kouji Hashimoto
- 当前专利权人： ARBLAST CO., LTD.,,Kouji Hashimoto
- 当前专利权人地址： JP Kobe-city JP Touon-shi
- 优先权： JP2004-069145 20040311
- 国际申请： PCT/JP05/02123 WO 20050214
- 主分类号： A61F2/14
- IPC分类号： A61F2/14 ; C12N5/02
摘要：
A corneal epithelial sheet having potential for the achievement of a favorable therapeutic effect and being highly safe in transplantation. The corneal epithelial sheet is constructed by: (a) preparing corneal epithelial cells; (b) separately culturing human fibroblasts in a collagen gel; (c) sowing or placing the corneal epithelial cells on the collagen gel; and (d) culturing and proliferating the corneal epithelial cells in the absence of xenogeneic animal cells.
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