发明申请
US20070292866A1 Diagnosing human diseases by detecting DNA methylation changes
审中-公开
通过检测DNA甲基化变化来诊断人类疾病
- 专利标题： Diagnosing human diseases by detecting DNA methylation changes
- 专利标题（中）： 通过检测DNA甲基化变化来诊断人类疾病
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申请号： US11634755申请日： 2006-12-06
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公开(公告)号： US20070292866A1公开(公告)日： 2007-12-20
- 发明人: Huajan Wang , Anthony Anisowicz , Richard Del Mastro , Hui Huang , Sergey Mamaev
- 申请人： Huajan Wang , Anthony Anisowicz , Richard Del Mastro , Hui Huang , Sergey Mamaev
- 专利权人： AMBERGEN, INC.
- 当前专利权人： AMBERGEN, INC.
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
This invention relates to methodologies that detect global changes in the methylation of human genomic DNA as well as changes in methylation in specific regions of the human genome. The methodologies have utility in the diagnosis, prognosis and monitoring of therapeutic treatment for any human disease. Further, the invention relates to methodologies that can detect global changes in the methylation of human genomic DNA that is a consequence of diet and/or dietary supplements. The invention also relates to identifying novel DNA methylation biomarkers that are associated with human disease.