A wireless remote control circuit with dual processing units and a method is provided, which includes a signal receiving unit, a first and a second processing unit. The first processing unit is connected to the signal receiving unit and switches between an activation mode and a sleep mode at a predefined time. The second processing unit is connected to the first processing unit and is preset in the sleep mode. The first processing unit provides a voltage to activate the signal receiving unit during the activation mode, and transmits a resume signal after obtaining a control signal. Then, the second processing unit enters an activation mode after it receives the resume signal, and enters the sleep mode again after its internal logic circuit completes its operation, so as to reduce the complexity of using a single processing unit to design a circuit and avoid huge power consumption of the circuit.