发明申请
- 专利标题： High Molecular Weight Derivatives of Vitamin K-Dependent Polypeptides
- 专利标题（中）： 维生素K依赖性多肽的高分子量衍生物
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申请号： US11696579申请日： 2007-04-04
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公开(公告)号： US20080004221A1公开(公告)日： 2008-01-03
- 发明人: Gary Nelsestuen , Ronald Bach , Matthew Stone , Stephen Harvey
- 申请人： Gary Nelsestuen , Ronald Bach , Matthew Stone , Stephen Harvey
- 主分类号： A61K38/36
- IPC分类号： A61K38/36 ; A61P7/00 ; C07K14/745
摘要：
Modifications of vitamin K-dependent polypeptides that lead to enhanced protein function on a weight or molar basis and/or increase of protein lifetime in the circulation are described. Both objectives are important for using vitamin K-dependent polypeptides for pro- and anti-coagulation therapies, as well as for other uses in the circulation.
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