发明申请
- 专利标题: Recombinant Microorganism
- 专利标题(中): 重组微生物
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申请号: US10578613申请日: 2004-11-05
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公开(公告)号: US20080009039A1公开(公告)日: 2008-01-10
- 发明人: Masatoshi Tohata , Kazuhisa Sawada , Katsuya Ozaki , Kazuo Kobayashi , Naotake Ogasawara
- 申请人: Masatoshi Tohata , Kazuhisa Sawada , Katsuya Ozaki , Kazuo Kobayashi , Naotake Ogasawara
- 申请人地址: JP Tokyo
- 专利权人: Kao Corporation
- 当前专利权人: Kao Corporation
- 当前专利权人地址: JP Tokyo
- 优先权: JP2003-379167 20031107
- 国际申请: PCT/JP04/16891 WO 20041105
- 主分类号: C12P21/04
- IPC分类号: C12P21/04 ; C12N1/21
摘要:
A recombinant microorganism obtained by transferring, into a host microorganism capable of producing protein or polypeptide with increased productivity, a gene encoding a protein or polypeptide, and a method for producing a protein or polypeptide by use of the recombinant microorganism. The recombinant microorganism is prepared by transferring, to a mutant strain of microorganism from which any of Bacillus subtilis genes comA, yopO, treR, yvbA, cspB, yvaN, yttP, yurK, yozA, licR, sigL, mntR, glcT, yvdE, ykvE, sir, rocR, ccpA, yaaT, yyaA, yycH, yacP, hprK, rsiX, yhdK, and yibO, or one or more genes functionally equivalent to any of these genes have been deleted or knocked out, a gene encoding a heterologous protein or polypeptide.
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