发明申请
US20080009076A1 METHODS OF IDENTIFYING COMPOUNDS THAT MODULATE IL-4 RECEPTOR-MEDIATED IGE SYNTHESIS UTILIZING A THIOREDOXIN-LIKE 32 KDA PROTEIN
有权
鉴定化合物的方法，该化合物调节IL-4受体介导的神经元合成使用类似噻二氮素的32 KDA蛋白
- 专利标题： METHODS OF IDENTIFYING COMPOUNDS THAT MODULATE IL-4 RECEPTOR-MEDIATED IGE SYNTHESIS UTILIZING A THIOREDOXIN-LIKE 32 KDA PROTEIN
- 专利标题（中）： 鉴定化合物的方法，该化合物调节IL-4受体介导的神经元合成使用类似噻二氮素的32 KDA蛋白
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申请号： US11608735申请日： 2006-12-08
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公开(公告)号： US20080009076A1公开(公告)日： 2008-01-10
- 发明人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人： Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： G01N33/567
- IPC分类号： G01N33/567
摘要：
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a thioredoxin-like 32 kDa protein (TXNL) as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
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