发明申请
- 专利标题: Microwell Array Chip and Its Manufacturing Method
- 专利标题(中): 微孔阵列芯片及其制造方法
-
申请号: US10573289申请日: 2004-09-22
-
公开(公告)号: US20080014631A1公开(公告)日: 2008-01-17
- 发明人: Atsushi Muraguchi , Hiroyuki Kishi , Yoshiharu Tokimitsu , Sachiko Kondo , Tsutomu Obata , Satoshi Fujiki , Yoshiyuki Yokoyama , Hirofumi Nabesawa , Sotohiro Takabayashi , Katsumi Tanino
- 申请人: Atsushi Muraguchi , Hiroyuki Kishi , Yoshiharu Tokimitsu , Sachiko Kondo , Tsutomu Obata , Satoshi Fujiki , Yoshiyuki Yokoyama , Hirofumi Nabesawa , Sotohiro Takabayashi , Katsumi Tanino
- 申请人地址: JP Toyama-shi JP Toyama-shi
- 专利权人: Sachiko KONDO,Yoshiharu TOKIMITSU
- 当前专利权人: Sachiko KONDO,Yoshiharu TOKIMITSU
- 当前专利权人地址: JP Toyama-shi JP Toyama-shi
- 优先权: JP2003-333363 20030925; JP2003-336771 20030929; JP2003-336793 20030929
- 国际申请: PCT/JP04/14285 WO 20040922
- 主分类号: C12M1/34
- IPC分类号: C12M1/34
摘要:
A microwell array chip having multiple microwells on a principal surface of a substrate, said microwells being of a shape and size permitting the storage of only a single organic cell in each microwell, wherein microwell markers are present on the same substrate surface as the openings of the microwells. A microwell array chip having multiple microwells on a principal surface of a substrate, said microwells being of a shape and size permitting the storage of only a single organic cell in each microwell, wherein protrusions are present in the openings of said microwells so as to narrow said openings. A method for manufacturing the microwell array chip. The method comprises the steps of: forming a film on at least one principal surface of a substrate; applying a resist coating on the film that has been formed; exposing the resist surface through a mask having a microwell pattern and removing uncured portions of resist; etching the exposed portions of said film and substrate to fabricate wells in the form of a microwell array; and removing the resist. A microwell array chip made of silicon and having multiple microwells, each microwell being used to store a single specimen organic cell, wherein each microwell is of a size and shape holding just one organic cell.