A refrigerant PTAC system, such as those commonly found in hotel rooms, can be selectively configured in a hardwire or wireless configuration with respect to its thermostat. The system is controlled in response to the better of two temperature sensors, which is determined based on the PTAC's configuration and the validity of the readings provided by the sensors. While the PTAC is controlled in response to a preferred temperature sensor, the alternate sensor may be monitored for diagnostics or other reasons. In the event that the preferred sensor fails to provide valid readings, the controller automatically switches to controlling the system in response to the alternate sensor. To minimize manufacturing costs and the variety of stocked parts, the PTAC's controller preferably includes two substantially identical transceivers.