发明申请
- 专利标题: Automated microscope for blood cell analysis
- 专利标题(中): 自动显微镜用于血细胞分析
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申请号: US11492372申请日: 2006-07-24
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公开(公告)号: US20080020128A1公开(公告)日: 2008-01-24
- 发明人: William John van Ryper , Tyler Cote , Steven I. Small , Amy P. Sheng , Ivan Hee Yiu Ma , Ronald Jones
- 申请人: William John van Ryper , Tyler Cote , Steven I. Small , Amy P. Sheng , Ivan Hee Yiu Ma , Ronald Jones
- 主分类号: G01N1/28
- IPC分类号: G01N1/28 ; G02B21/00 ; B05D3/00
摘要:
An apparatus and method of automated blood cell analysis uses technologies from other systems to create a new, robust, improved type of automated microscope, which uses electronic motors and a closed loop control system to minimize ambient factors, such as jarring and temperature changes. Pre-stained blood smear slides are first coated with a thin film of oil and are loaded into a carousel from which they can individually be analyzed. The slides are moved under a low magnification microscope; an optimal area of examination is determined; a focal plane map is calculated for that area, and the positions of white blood cell candidates are computed. The slide is then moved under a high power microscope where a refined focal plane map is computed and the individual white blood cell candidates are imaged. The cells are preclassified and the images are made available for analysis by the technician. Additionally, samples of red blood cells, equivalent to what the technician would do manually, are imaged and presented to the technician for evaluation. The technician may make notes on those cells, both red and white blood cells and archive them.
公开/授权文献
- US08067245B2 Automated microscope for blood cell analysis 公开/授权日:2011-11-29
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