发明申请
- 专利标题： PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF
- 专利标题（中）： 作为杀虫剂和杀虫剂的激活剂的药物化合物及其用途
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申请号： US11773293申请日： 2007-07-03
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公开(公告)号： US20080020985A1公开(公告)日： 2008-01-24
- 发明人: Sui Xiong Cai , Mark Anderson , Adam Willardsen , Songchun Jiang , Robert Halter , Rachel Slade , Yevgeniya Klimova
- 申请人： Sui Xiong Cai , Mark Anderson , Adam Willardsen , Songchun Jiang , Robert Halter , Rachel Slade , Yevgeniya Klimova
- 申请人地址： US UT Salt Lake City 84108 US CA San Diego 92121
- 专利权人： Myriad Genetics, Inc.,Cytovia, Inc.
- 当前专利权人： Myriad Genetics, Inc.,Cytovia, Inc.
- 当前专利权人地址： US UT Salt Lake City 84108 US CA San Diego 92121
- 主分类号： A61K31/53
- IPC分类号： A61K31/53 ; A61K31/502 ; A61K31/66 ; A61K31/704 ; A61K31/7076 ; A61K38/08 ; A61P29/00 ; A61P31/12 ; A61P35/00 ; A61P37/00 ; C07D237/34 ; C07D253/08
摘要：
Disclosed are 1-arylamino-phthalazines, 4-arylamino-benzo[d][1,2,3]triazines, and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
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