发明申请
- 专利标题： Control of gene expression
- 专利标题（中）： 基因表达控制
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申请号： US11712311申请日： 2007-02-28
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公开(公告)号： US20080026985A1公开(公告)日： 2008-01-31
- 发明人: Lakjaya Buluwela , Simak Ali
- 申请人： Lakjaya Buluwela , Simak Ali
- 申请人地址： GB London
- 专利权人： Imperial Innovations Limited
- 当前专利权人： Imperial Innovations Limited
- 当前专利权人地址： GB London
- 优先权： JP9915126.8 19990630; GBPCT/GB00/02497 20000628
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; A61K38/00 ; A61P43/00 ; C12N1/00 ; C12N1/21 ; C12N15/09 ; C12N5/04 ; C12N5/06 ; C12N5/10
摘要：
A method of suppressing the expression of a selected gene in a eukaryotic cell the method comprising introducing into the cell (a) a polypeptide comprising a DNA binding portion which binds to a site at or associated with the selected gene which site is present in a plant or animal genome and a chromatin inactivation portion, or (b) a polynucleotide encoding said polypeptide.
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