- 专利标题: COMPOUNDS AND THERAPEUTICAL USE THEREOF
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申请号: US11779086申请日: 2007-07-17
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公开(公告)号: US20080032974A1公开(公告)日: 2008-02-07
- 发明人: Sui Xiong Cai , Nilantha Sirisoma , Azra Pervin , John Drewe , Shailaja Kasibhatla , Songchun Jiang , Hong Zhang , Chris Pleiman , Vijay Baichwal , John Manfredi , Leena Bhoite
- 申请人: Sui Xiong Cai , Nilantha Sirisoma , Azra Pervin , John Drewe , Shailaja Kasibhatla , Songchun Jiang , Hong Zhang , Chris Pleiman , Vijay Baichwal , John Manfredi , Leena Bhoite
- 申请人地址: US UT Salt Lake City 84108 US CA San Diego 92121
- 专利权人: Myriad Genetics, Incorporated,Cytovia, Inc.
- 当前专利权人: Myriad Genetics, Incorporated,Cytovia, Inc.
- 当前专利权人地址: US UT Salt Lake City 84108 US CA San Diego 92121
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; A61K31/52 ; A61K31/5377 ; A61P31/10 ; A61P35/00 ; C07D239/94 ; C07D401/12 ; C07D413/12 ; C07D473/16
摘要:
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.