Invention Application
US20080038725A1 Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations
审中-公开
检测单个细胞中的核酸并鉴定来自大异质细胞群体的稀有细胞的方法
- Patent Title: Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations
- Patent Title (中): 检测单个细胞中的核酸并鉴定来自大异质细胞群体的稀有细胞的方法
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Application No.: US11471278Application Date: 2006-06-19
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Publication No.: US20080038725A1Publication Date: 2008-02-14
- Inventor: Yuling Luo , Shiping Chen
- Applicant: Yuling Luo , Shiping Chen
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Methods of detecting multiple nucleic acid targets in single cells through indirect capture of labels to the nucleic acids are provided. Methods of assaying the relative levels of nucleic acid targets through normalization to levels of reference nucleic acids are also provided. Methods of detecting individual cells, particularly rare cells from large heterogeneous cell populations, through detection of nucleic acids are described. Related compositions, systems, and kits are also provided.
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