发明申请
US20080045517A1 6H-THIENO[2,3-b]PYRROLE DERIVATIVES AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE (GNRH)
失效
6H-THIENO [2,3-b]吡咯衍生物作为角叉菜胶释放激素（GNRH）的拮抗剂
![6H-THIENO[2,3-b]PYRROLE DERIVATIVES AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE (GNRH)](/docs/US/2008-02-21/US20080045517A1/abs.jpg.600x600.jpg)
- 专利标题： 6H-THIENO[2,3-b]PYRROLE DERIVATIVES AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE (GNRH)
- 专利标题（中）： 6H-THIENO [2,3-b]吡咯衍生物作为角叉菜胶释放激素（GNRH）的拮抗剂
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申请号： US11752007申请日： 2007-05-22
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公开(公告)号： US20080045517A1公开(公告)日： 2008-02-21
- 发明人: Kevin Foote , Zbigniew Matusiak , Alexander Dossetter , Jean Claude Arnould , Maryannick Lamorlette , Benedicte Delouvrie , Annie Hamon
- 申请人： Kevin Foote , Zbigniew Matusiak , Alexander Dossetter , Jean Claude Arnould , Maryannick Lamorlette , Benedicte Delouvrie , Annie Hamon
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 优先权： EP02292074.8 20020821
- 主分类号： A61K31/541
- IPC分类号： A61K31/541 ; A61K31/407 ; A61K31/44 ; A61K31/445 ; A61P35/00 ; C07D221/00 ; C07D277/02 ; C07D295/00 ; C07D279/10 ; C07D239/24 ; C07D213/02 ; A61K31/496 ; A61K31/506 ; A61K31/5377
![6H-THIENO[2,3-b]PYRROLE DERIVATIVES AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE (GNRH)](/abs-image/US/2008/02/21/US20080045517A1/abs.jpg.150x150.jpg)
摘要：
The invention relates to a group of novel thieno-pyrrole compounds of Formula (I): wherein: R1, R2, R3, R4 and R5 are as defined in the specification, which are useful as gonadotrophin releasing hormone antagonists. The invention also relates to pharmaceutical formulations of said compounds, methods of treatment using said compounds and to processes for the preparation of said compounds.
公开/授权文献
- US07547722B2 Chemical compounds 公开/授权日：2009-06-16
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