发明申请
US20080050379A1 Cancer gene determination and therapeutic screening using signature gene sets
审中-公开
癌基因测定和使用签名基因组的治疗筛选
- 专利标题： Cancer gene determination and therapeutic screening using signature gene sets
- 专利标题（中）： 癌基因测定和使用签名基因组的治疗筛选
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申请号： US11881252申请日： 2007-07-26
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公开(公告)号： US20080050379A1公开(公告)日： 2008-02-28
- 发明人: Paul Young , Meena Augustus , Kenneth Carter , Reinhard Ebner , Gregory Endress , Stephen Horrigan , Daniel Soppet , Zoe Weaver
- 申请人： Paul Young , Meena Augustus , Kenneth Carter , Reinhard Ebner , Gregory Endress , Stephen Horrigan , Daniel Soppet , Zoe Weaver
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K31/00 ; A61P43/00 ; C07K16/18 ; C12Q1/68 ; C40B30/06 ; G01N33/566
摘要：
Processes for assaying potential antitumor agents based on their modulation of the expression of specified genes, or sets, of suspected cancer cell genes are disclosed, along with methods for diagnosing cancerous, or potentially cancerous, conditions as a result of the expression, or patterns of expression, of such genes, or sets of genes. Also disclosed are methods for determining functionally related genes, or gene sets, as well as methods for treating cancer based on targeting expression products of such genes, or gene sets, and determining genes involved in the cancerous process.
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