发明申请
- 专利标题: Production of viruses, viral isolates and vaccines
- 专利标题(中): 生产病毒,病毒分离物和疫苗
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申请号: US11879422申请日: 2007-07-16
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公开(公告)号: US20080050403A1公开(公告)日: 2008-02-28
- 发明人: Giuseppe Marzio , Maria Pau , Dirk Opstelten , Alphonsus Gerardus Uytdehaag
- 申请人: Giuseppe Marzio , Maria Pau , Dirk Opstelten , Alphonsus Gerardus Uytdehaag
- 专利权人: Crucell Holland B.V.
- 当前专利权人: Crucell Holland B.V.
- 优先权: NLPCT/NL01/00892 20011207; EP02075327.3 20020125
- 主分类号: C12N7/01
- IPC分类号: C12N7/01 ; A61K39/13 ; A61K39/155 ; A61K39/235 ; A61P37/04 ; C12N15/00
摘要:
The present invention discloses methods for producing and/or propagating virus particles, such as influenza virus particles, that are present in a virus isolate obtained from an infected subject by contacting a host cell with a virus particle and culturing the cell under conditions conducive to propagation of the virus particle. The invention also provides a method for selective propagation of a set of virus particles, such as influenza virus particles present in an influenza isolate, which have an affinity for receptors comprising a specific glycosylation residue.
公开/授权文献
- US08802417B2 Production of viruses, viral isolates and vaccines 公开/授权日:2014-08-12
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