发明申请
- 专利标题: Inhibition of VEGF Translation
- 专利标题(中): VEGF翻译的抑制作用
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申请号: US11765871申请日: 2007-06-20
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公开(公告)号: US20080064683A1公开(公告)日: 2008-03-13
- 发明人: Liangxian Cao , Thomas Davis , Charles Romfo , Christopher Trotta
- 申请人: Liangxian Cao , Thomas Davis , Charles Romfo , Christopher Trotta
- 主分类号: A61K31/437
- IPC分类号: A61K31/437 ; A61K31/497 ; A61K31/5377 ; A61K31/541 ; A61K31/551 ; A61P19/00 ; A61P3/00 ; A61P35/00 ; C12Q1/68
摘要:
In accordance with the present invention, methods for inhibiting the translation of VEGF and methods for decreasing VEGF level by inhibiting VEGF translation are provided. In another aspect of the invention, compounds that inhibit the 5′-UTR-dependent translation of VEGF and methods for identifying such compounds are provided.
公开/授权文献
- US08076353B2 Inhibition of VEGF translation 公开/授权日:2011-12-13
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