发明申请
US20080070876A1 Gaba-Steroid Antagonists And Their Use For The Treatment Of Cns Disorders
有权
Gaba类固醇拮抗剂及其用于治疗Cns疾病的用途
- 专利标题： Gaba-Steroid Antagonists And Their Use For The Treatment Of Cns Disorders
- 专利标题（中）： Gaba类固醇拮抗剂及其用于治疗Cns疾病的用途
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申请号： US11791160申请日： 2005-11-07
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公开(公告)号： US20080070876A1公开(公告)日： 2008-03-20
- 发明人: Torbjorn Backstrom , Per Lundgren , Ming-De Wang
- 申请人： Torbjorn Backstrom , Per Lundgren , Ming-De Wang
- 申请人地址： SE Umea 907 38
- 专利权人： UMECRINE AB
- 当前专利权人： UMECRINE AB
- 当前专利权人地址： SE Umea 907 38
- 国际申请： PCT/SE05/01671 WO 20051107
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; A61P25/00
摘要：
Compounds exhibiting 3alpha-hydroxy-5alpha/beta-steroid blocking action with no or only low antagonism against the gamma-aminobutyric acid (A) receptor (GABA-A), and compounds exhibiting partial antagonism against said receptor are presented. Methods for the prevention, treatment and/or alleviation of various CNS-disorders are suggested, as well as pharmaceutical compositions for such use.
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