发明申请
- 专利标题: Novel Substituted Imidazole Derivative
- 专利标题(中): 新型替代咪唑衍生物
-
申请号: US11661486申请日: 2005-08-30
-
公开(公告)号: US20080070894A1公开(公告)日: 2008-03-20
- 发明人: Mikako Kawamura , Takashi Hashihayata , Satoshi Sunami , Tetsuya Sugimoto , Fuyuki Yamamoto , Yoshiyuki Sato , Kaori Kamijo , Morihiro Mitsuya , Yoshikazu Iwasawa , Hideya Komatani
- 申请人: Mikako Kawamura , Takashi Hashihayata , Satoshi Sunami , Tetsuya Sugimoto , Fuyuki Yamamoto , Yoshiyuki Sato , Kaori Kamijo , Morihiro Mitsuya , Yoshikazu Iwasawa , Hideya Komatani
- 优先权: JP2004-251500 20040831
- 国际申请: PCT/JP05/16187 WO 20050830
- 主分类号: A61K31/397
- IPC分类号: A61K31/397 ; A61K31/496 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/52 ; A61K31/5377 ; A61K31/5513 ; A61P35/00 ; C07D237/06 ; C07D239/24 ; C07D243/14 ; C07D295/00 ; C07D473/00
摘要:
The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1′, R2, R2′, R3, R3′, R4, and R4′, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8′, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.
公开/授权文献
- US07718801B2 Substituted imidazole derivative 公开/授权日:2010-05-18
信息查询