发明申请
- 专利标题： Anti-IL-6 monoclonal antibodies and uses thereof
- 专利标题（中）： 抗IL-6单克隆抗体及其用途
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申请号： US11882751申请日： 2007-08-03
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公开(公告)号： US20080075726A1公开(公告)日： 2008-03-27
- 发明人: Ernest Smith , Wei Wang
- 申请人： Ernest Smith , Wei Wang
- 申请人地址： US NY Rochester
- 专利权人： Vaccinex, Inc.
- 当前专利权人： Vaccinex, Inc.
- 当前专利权人地址： US NY Rochester
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P35/00 ; C07K16/00 ; C12N15/13 ; C12N15/85 ; C12N5/10 ; C12P21/08
摘要：
The present invention provides novel monoclonal antibodies that bind specifically to IL-6. The antibodies of the invention comprise a variable heavy chain (VH) region selected from any of the VH regions disclosed herein as well as amino acid variants thereof, and/or a variable light chain (VL) region selected from any of the VL regions disclosed herein as well as amino acid variants thereof. The invention also provides methods of treating diseases and disorders associated with IL-6 expression and/or activity.
公开/授权文献
- US07919095B2 Anti-IL-6 monoclonal antibodies 公开/授权日：2011-04-05
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