发明申请
US20080076934A1 (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1- (pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition
审中-公开
(R)-2-(4-脒基苯基氨基甲基)-1-甲基-5- [1-(羧甲基氨基)-1-(吡咯烷基羰基) - 乙基] - 苯并咪唑,其一盐酸盐,其制备和用作药物组合物
- 专利标题: (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1- (pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition
- 专利标题(中): (R)-2-(4-脒基苯基氨基甲基)-1-甲基-5- [1-(羧甲基氨基)-1-(吡咯烷基羰基) - 乙基] - 苯并咪唑,其一盐酸盐,其制备和用作药物组合物
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申请号: US11865949申请日: 2007-10-02
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公开(公告)号: US20080076934A1公开(公告)日: 2008-03-27
- 发明人: Guenter Linz , Peter Sieger , Gunnar Schreiner , Werner Rall , Rolf Schmid
- 申请人: Guenter Linz , Peter Sieger , Gunnar Schreiner , Werner Rall , Rolf Schmid
- 优先权: DE10227666.8 20020620
- 主分类号: C07D403/02
- IPC分类号: C07D403/02
摘要:
Crystalline forms of the compounds (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole and the monohydrochloride thereof, processes for the preparation thereof and the use thereof as pharmaceutical compositions.
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